Reconstructing differentiation networks and their regulation from time series single-cell expression data

Generating detailed and accurate organogenesis models using single-cell RNA-seq data remains a major challenge. Current methods have relied primarily on the assumption that descendant cells are similar to their parents in terms of gene expression levels. These assumptions do not always hold for in v...

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Bibliographic Details
Published in:Genome Res
Main Authors: Ding, Jun, Aronow, Bruce J., Kaminski, Naftali, Kitzmiller, Joseph, Whitsett, Jeffrey A., Bar-Joseph, Ziv
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2018
Subjects:
Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848617/
https://ncbi.nlm.nih.gov/pubmed/29317474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.225979.117
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