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Continuous-state HMMs for modeling time-series single-cell RNA-Seq data

MOTIVATION: Methods for reconstructing developmental trajectories from time-series single-cell RNA-Seq (scRNA-Seq) data can be largely divided into two categories. The first, often referred to as pseudotime ordering methods are deterministic and rely on dimensionality reduction followed by an orderi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformatics
Hauptverfasser: Lin, Chieh, Bar-Joseph, Ziv
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853676/
https://ncbi.nlm.nih.gov/pubmed/31038684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz296
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