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SMARTS: reconstructing disease response networks from multiple individuals using time series gene expression data

Motivation: Current methods for reconstructing dynamic regulatory networks are focused on modeling a single response network using model organisms or cell lines. Unlike these models or cell lines, humans differ in their background expression profiles due to age, genetics and life factors. In additio...

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Vydáno v:Bioinformatics
Hlavní autoři: Wise, Aaron, Bar-Joseph, Ziv
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393515/
https://ncbi.nlm.nih.gov/pubmed/25480376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu800
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