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SMARTS: reconstructing disease response networks from multiple individuals using time series gene expression data

Motivation: Current methods for reconstructing dynamic regulatory networks are focused on modeling a single response network using model organisms or cell lines. Unlike these models or cell lines, humans differ in their background expression profiles due to age, genetics and life factors. In additio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformatics
Hauptverfasser: Wise, Aaron, Bar-Joseph, Ziv
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393515/
https://ncbi.nlm.nih.gov/pubmed/25480376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu800
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