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glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis

The interconversion of cell lineages via transdifferentiation is an adaptive mode of tissue regeneration and an appealing therapeutic target. However, its clinical exploitation is contingent upon the discovery of contextual regulators of cell fate acquisition and maintenance. In murine models of dia...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Ye, Lihua, Robertson, Morgan A., Hesselson, Daniel, Stainier, Didier Y. R., Anderson, Ryan M.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392596/
https://ncbi.nlm.nih.gov/pubmed/25852199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117911
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