A New Way for Beta Cell Neogenesis: Transdifferentiation from Alpha Cells Induced by Glucagon-Like Peptide 1

Recent studies showed that alpha cells, especially immature cells and proalpha cells, might be the precursors of beta cells. Exposure to glucagon-like peptide 1 (GLP1) can ameliorate hyperglycemia in diabetic mice and restore the beta cell mass. In the present study, we adopted single high-dose (60 ...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Zhang, Zhen, Hu, Yinghui, Xu, Ningning, Zhou, Wenjun, Yang, Lei, Chen, Rongping, Yang, Rui, Sun, Jia, Chen, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436340/
https://ncbi.nlm.nih.gov/pubmed/31001561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2583047
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