Increased alpha and beta cell mass during mouse pregnancy is not dependent on transdifferentiation

Maternal pancreatic beta-cell mass (BCM) increases during pregnancy to compensate for relative insulin resistance. If BCM expansion is suboptimal, gestational diabetes mellitus can develop. Alpha-cell mass (ACM) also changes during pregnancy, but there is a lack of information about α-cell plasticit...

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Udgivet i:Exp Biol Med (Maywood)
Main Authors: Szlapinski, Sandra K, Bennett, Jamie, Strutt, Brenda J, Hill, David J
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934144/
https://ncbi.nlm.nih.gov/pubmed/33231513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220972686
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