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An increase in immature β-cells lacking Glut2 precedes the expansion of β-cell mass in the pregnant mouse
A compensatory increase in β-cell mass occurs during pregnancy to counter the associated insulin resistance, and a failure in adaptation is thought to contribute to gestational diabetes. Insulin-expressing but glucose-transporter-2-low (Ins(+)Glut2(LO)) progenitor cells are present in mouse and huma...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533342/ https://ncbi.nlm.nih.gov/pubmed/28753672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182256 |
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