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glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis
The interconversion of cell lineages via transdifferentiation is an adaptive mode of tissue regeneration and an appealing therapeutic target. However, its clinical exploitation is contingent upon the discovery of contextual regulators of cell fate acquisition and maintenance. In murine models of dia...
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| Publié dans: | Development |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392596/ https://ncbi.nlm.nih.gov/pubmed/25852199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117911 |
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