Hepatocyte Growth Factor Signaling in Intrapancreatic Ductal Cells Drives Pancreatic Morphogenesis

In a forward genetic screen for regulators of pancreas development in zebrafish, we identified donut(s908), a mutant which exhibits failed outgrowth of the exocrine pancreas. The s908 mutation leads to a leucine to arginine substitution in the ectodomain of the hepatocyte growth factor (HGF) tyrosin...

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Detalhes bibliográficos
Main Authors: Anderson, Ryan M., Delous, Marion, Bosch, Justin A., Ye, Lihua, Robertson, Morgan A., Hesselson, Daniel, Stainier, Didier Y. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723531/
https://ncbi.nlm.nih.gov/pubmed/23935514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003650
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