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Hepatocyte Growth Factor Signaling in Intrapancreatic Ductal Cells Drives Pancreatic Morphogenesis
In a forward genetic screen for regulators of pancreas development in zebrafish, we identified donut(s908), a mutant which exhibits failed outgrowth of the exocrine pancreas. The s908 mutation leads to a leucine to arginine substitution in the ectodomain of the hepatocyte growth factor (HGF) tyrosin...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3723531/ https://ncbi.nlm.nih.gov/pubmed/23935514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003650 |
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