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Distinct populations of quiescent and proliferative pancreatic β-cells identified by HOTcre mediated labeling

Pancreatic β-cells are critical regulators of glucose homeostasis, and they vary dramatically in their glucose stimulated metabolic response and levels of insulin secretion. It is unclear whether these parameters are influenced by the developmental origin of individual β-cells. Using HOTcre, a Cre-b...

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Detalles Bibliográficos
Main Authors: Hesselson, Daniel, Anderson, Ryan M., Beinat, Marine, Stainier, Didier Y. R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736433/
https://ncbi.nlm.nih.gov/pubmed/19706417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906348106
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