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Suppression of Ptf1a activity induces acinar to endocrine conversion

Pluripotent embryonic cells become progressively lineage-restricted during development in a process that culminates in the differentiation of stable organ specific cell types that perform specialized functions. Terminally-differentiated pancreatic acinar cells do not have the innate capacity to cont...

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Main Authors: Hesselson, Daniel, Anderson, Ryan M., Stainier, Didier Y.R.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081919/
https://ncbi.nlm.nih.gov/pubmed/21497092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.03.041
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