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Suppression of Ptf1a activity induces acinar to endocrine conversion
Pluripotent embryonic cells become progressively lineage-restricted during development in a process that culminates in the differentiation of stable organ specific cell types that perform specialized functions. Terminally-differentiated pancreatic acinar cells do not have the innate capacity to cont...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081919/ https://ncbi.nlm.nih.gov/pubmed/21497092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.03.041 |
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