Abnormal regulation of glucagon secretion by human islet alpha cells in the absence of beta cells

BACKGROUND: The understanding of the regulation of glucagon secretion by pancreatic islet α-cells remains elusive. We aimed to develop an in vitro model for investigating the function of human α-cells under direct influence of glucose and other potential regulators. METHODS: Highly purified human α-...

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Bibliografiska uppgifter
I publikationen:EBioMedicine
Huvudupphovsmän: Liu, Wei, Kin, Tatsuya, Ho, Siuhong, Dorrell, Craig, Campbell, Sean R., Luo, Ping, Chen, Xiaojuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2019
Ämnen:
Research paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921359/
https://ncbi.nlm.nih.gov/pubmed/31780397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.11.018
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