HUMAN BETA CELLS PRODUCE AND RELEASE SEROTONIN TO INHIBIT GLUCAGON SECRETION FROM ALPHA CELLS

In the pancreatic islet serotonin is an autocrine signal increasing beta cell mass during metabolic challenges such as those associated with pregnancy or high-fat diet. It is still unclear if serotonin is relevant for regular islet physiology and hormone secretion. Here we show that human beta cells...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Almaça, Joana, Molina, Judith, Menegaz, Danusa, Pronin, Alexey N., Tamayo, Alejandro, Slepak, Vladlen, Berggren, Per-Olof, Caicedo, Alejandro
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217294/
https://ncbi.nlm.nih.gov/pubmed/28009296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.072
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