HUMAN BETA CELLS PRODUCE AND RELEASE SEROTONIN TO INHIBIT GLUCAGON SECRETION FROM ALPHA CELLS

In the pancreatic islet serotonin is an autocrine signal increasing beta cell mass during metabolic challenges such as those associated with pregnancy or high-fat diet. It is still unclear if serotonin is relevant for regular islet physiology and hormone secretion. Here we show that human beta cells...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Almaça, Joana, Molina, Judith, Menegaz, Danusa, Pronin, Alexey N., Tamayo, Alejandro, Slepak, Vladlen, Berggren, Per-Olof, Caicedo, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217294/
https://ncbi.nlm.nih.gov/pubmed/28009296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.072
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