HUMAN BETA CELLS PRODUCE AND RELEASE SEROTONIN TO INHIBIT GLUCAGON SECRETION FROM ALPHA CELLS

In the pancreatic islet serotonin is an autocrine signal increasing beta cell mass during metabolic challenges such as those associated with pregnancy or high-fat diet. It is still unclear if serotonin is relevant for regular islet physiology and hormone secretion. Here we show that human beta cells...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Almaça, Joana, Molina, Judith, Menegaz, Danusa, Pronin, Alexey N., Tamayo, Alejandro, Slepak, Vladlen, Berggren, Per-Olof, Caicedo, Alejandro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217294/
https://ncbi.nlm.nih.gov/pubmed/28009296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.072
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