Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming human beta cell function

Acetylcholine is a neurotransmitter that plays a major role in the function of the insulin secreting pancreatic beta cell(1,2). Parasympathetic innervation of the endocrine pancreas, the islets of Langerhans, has been shown to provide cholinergic input to the beta cell in several species(1,3,4), but...

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Main Authors: Rodriguez-Diaz, Rayner, Dando, Robin, Jacques-Silva, M. Caroline, Fachado, Alberto, Molina, Judith, Abdulreda, Midhat, Ricordi, Camillo, Roper, Stephen D., Berggren, Per-Olof, Caicedo, Alejandro
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132226/
https://ncbi.nlm.nih.gov/pubmed/21685896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2371
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