A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

NAD metabolism regulates diverse biological processes, including ageing, circadian rhythm and axon survival. Axons depend on the activity of the central enzyme in NAD biosynthesis, nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2), for their maintenance and degenerate rapidly when this acti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Differ
Päätekijät: Di Stefano, M, Nascimento-Ferreira, I, Orsomando, G, Mori, V, Gilley, J, Brown, R, Janeckova, L, Vargas, M E, Worrell, L A, Loreto, A, Tickle, J, Patrick, J, Webster, J R M, Marangoni, M, Carpi, F M, Pucciarelli, S, Rossi, F, Meng, W, Sagasti, A, Ribchester, R R, Magni, G, Coleman, M P, Conforti, L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392071/
https://ncbi.nlm.nih.gov/pubmed/25323584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.164
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia