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Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome
The pathogenesis of atypical hemolytic uremic syndrome (aHUS) is strongly linked to dysregulation of the alternative pathway of the complement system. Mutations in complement genes have been identified in about two-thirds of cases, with 5% to 15% being in C3. In this study, 23 aHUS-associated geneti...
Zapisane w:
| Wydane w: | Blood |
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| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Hematology
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392009/ https://ncbi.nlm.nih.gov/pubmed/25608561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-609073 |
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