Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease

INTRODUCTION: Scurfy mice are deficient in regulatory T cells (Tregs), develop a severe, generalized autoimmune disorder that can affect almost every organ and die at an early age. Some of these manifestations resemble those found in systemic lupus erythematosus (SLE). In addition, active SLE is ass...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Res Ther
Prif Awduron: Hadaschik, Eva N, Wei, Xiaoying, Leiss, Harald, Heckmann, Britta, Niederreiter, Birgit, Steiner, Günter, Ulrich, Walter, Enk, Alexander H, Smolen, Josef S, Stummvoll, Georg H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391674/
https://ncbi.nlm.nih.gov/pubmed/25890083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0538-0
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