MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristane-induced lupus

OBJECTIVE: We herein examine the role of endogenous miR155 in the development of systemic manifestations in pristane induced lupus. MATERIALS AND METHODS: Systemic lupus in miR155-deficient and wild type mice was induced upon injection of pristane and analyzed after 8 months, PBS-injected mice serve...

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Publicat a:PLoS One
Autors principals: Leiss, Harald, Salzberger, Wilhelm, Jacobs, Barbara, Gessl, Irina, Kozakowski, Nicolas, Blüml, Stephan, Puchner, Antonia, Kiss, Attila, Podesser, Bruno K., Smolen, Josef S., Stummvoll, Georg H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515414/
https://ncbi.nlm.nih.gov/pubmed/28719617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181015
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