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Stochastic Tunneling and Metastable States During the Somatic Evolution of Cancer

Tumors initiate when a population of proliferating cells accumulates a certain number and type of genetic and/or epigenetic alterations. The population dynamics of such sequential acquisition of (epi)genetic alterations has been the topic of much investigation. The phenomenon of stochastic tunneling...

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Bibliografische gegevens
Gepubliceerd in:Genetics
Hoofdauteurs: Ashcroft, Peter, Michor, Franziska, Galla, Tobias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391561/
https://ncbi.nlm.nih.gov/pubmed/25624316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.171553
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