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Stochastic Tunneling of Two Mutations in a Population of Cancer Cells
Cancer initiation, progression, and the emergence of drug resistance are driven by specific genetic and/or epigenetic alterations such as point mutations, structural alterations, DNA methylation and histone modification changes. These alterations may confer advantageous, deleterious or neutral effec...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694076/ https://ncbi.nlm.nih.gov/pubmed/23840359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065724 |
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