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Stochastic elimination of cancer cells.

Tissues of multicellular organisms consist of stem cells and differentiated cells. Stem cells divide to produce new stem cells or differentiated cells. Differentiated cells divide to produce new differentiated cells. We show that such a tissue design can reduce the rate of fixation of mutations that...

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Détails bibliographiques
Auteurs principaux: Michor, Franziska, Nowak, Martin A, Frank, Steven A, Iwasa, Yoh
Format: Artigo
Langue:Inglês
Publié: 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1691466/
https://ncbi.nlm.nih.gov/pubmed/14561289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2003.2483
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