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The linear process of somatic evolution

Cancer is the consequence of an unwanted evolutionary process. Cells receive mutations that alter their phenotype. Especially dangerous are those mutations that increase the net reproductive rate of cells, thereby leading to neoplasia and later to cancer. The standard models of evolutionary dynamics...

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Detalhes bibliográficos
Main Authors: Nowak, Martin A., Michor, Franziska, Iwasa, Yoh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299861/
https://ncbi.nlm.nih.gov/pubmed/14657359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2535419100
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