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The linear process of somatic evolution
Cancer is the consequence of an unwanted evolutionary process. Cells receive mutations that alter their phenotype. Especially dangerous are those mutations that increase the net reproductive rate of cells, thereby leading to neoplasia and later to cancer. The standard models of evolutionary dynamics...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299861/ https://ncbi.nlm.nih.gov/pubmed/14657359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2535419100 |
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