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Evolution of Resistance During Clonal Expansion
Acquired drug resistance is a major limitation for cancer therapy. Often, one genetic alteration suffices to confer resistance to an otherwise successful therapy. However, little is known about the dynamics of the emergence of resistant tumor cells. In this article, we consider an exponentially grow...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Copyright © 2006 by the Genetics Society of America
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456382/ https://ncbi.nlm.nih.gov/pubmed/16636113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.049791 |
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