Nalaganje...
Genetic instability and clonal expansion
Inactivation of tumor suppressor genes can lead to clonal expansion. We study the evolutionary dynamics of this process and calculate the probability that inactivation of a tumor suppressor gene is preceded by mutations in genes that confer genetic instability. Unstable cells might have a slower rat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286117/ https://ncbi.nlm.nih.gov/pubmed/16405914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2005.11.012 |
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