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Stochastic Tunneling and Metastable States During the Somatic Evolution of Cancer
Tumors initiate when a population of proliferating cells accumulates a certain number and type of genetic and/or epigenetic alterations. The population dynamics of such sequential acquisition of (epi)genetic alterations has been the topic of much investigation. The phenomenon of stochastic tunneling...
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| Опубликовано в: : | Genetics |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391561/ https://ncbi.nlm.nih.gov/pubmed/25624316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.171553 |
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