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A NONPEPTIDE ANGIOTENSIN II TYPE 2 RECEPTOR AGONIST PREVENTS RENAL INFLAMMATION IN EARLY DIABETES

We hypothesized that direct AT2R stimulation improves albuminuria in diabetes by preventing renal inflammation and improving oxidative stress. Normoglycemic controls (NC) and streptozotocin-induced diabetes Sprague-Dawley rats (DM) were treated for 4 weeks with vehicle (V) or the AT2R agonist Compou...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Matavelli, Luis C., Zatz, Roberto, Siragy, Helmy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390440/
https://ncbi.nlm.nih.gov/pubmed/25590749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000207
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