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A NONPEPTIDE ANGIOTENSIN II TYPE 2 RECEPTOR AGONIST PREVENTS RENAL INFLAMMATION IN EARLY DIABETES

We hypothesized that direct AT2R stimulation improves albuminuria in diabetes by preventing renal inflammation and improving oxidative stress. Normoglycemic controls (NC) and streptozotocin-induced diabetes Sprague-Dawley rats (DM) were treated for 4 weeks with vehicle (V) or the AT2R agonist Compou...

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Détails bibliographiques
Publié dans:J Cardiovasc Pharmacol
Auteurs principaux: Matavelli, Luis C., Zatz, Roberto, Siragy, Helmy M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390440/
https://ncbi.nlm.nih.gov/pubmed/25590749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000207
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