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COMBINED ALISKIREN AND AMLODIPINE REDUCE ALBUMINURIA VIA REDUCTION IN RENAL INFLAMMATION IN DIABETIC RATS

We hypothesized that compared to hydrochlorothiazide (HCTZ), the renin inhibitor aliskiren (ALISK) or amlodipine (AMLO) and their combination reduce albuminuria via reduction in renal inflammation, independent of BP changes. We studied normal and streptozotocin induced diabetic (DM) Sprague-Dawley r...

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Detalhes bibliográficos
Main Authors: Matavelli, Luis C., Huang, Jiqian, Siragy, Helmy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296909/
https://ncbi.nlm.nih.gov/pubmed/22075749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31823fc3f5
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