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COMBINED ALISKIREN AND AMLODIPINE REDUCE ALBUMINURIA VIA REDUCTION IN RENAL INFLAMMATION IN DIABETIC RATS

We hypothesized that compared to hydrochlorothiazide (HCTZ), the renin inhibitor aliskiren (ALISK) or amlodipine (AMLO) and their combination reduce albuminuria via reduction in renal inflammation, independent of BP changes. We studied normal and streptozotocin induced diabetic (DM) Sprague-Dawley r...

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Bibliografische gegevens
Hoofdauteurs: Matavelli, Luis C., Huang, Jiqian, Siragy, Helmy M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296909/
https://ncbi.nlm.nih.gov/pubmed/22075749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31823fc3f5
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