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REDUCTION OF ALDOSTERONE PRODUCTION IMPROVES RENAL OXIDATIVE STRESS AND FIBROSIS IN DIABETIC RATS

Aldosterone is increased in diabetes and contributes to the development of diabetic nephropathy. We hypothesized that reduction in aldosterone production in diabetes by amlodipine or aliskiren improves diabetic kidney disease by attenuating renal oxidative stress and fibrosis. Normoglycemic and stre...

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Detalhes bibliográficos
Main Authors: Matavelli, Luis C., Siragy, Helmy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538933/
https://ncbi.nlm.nih.gov/pubmed/23011470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e318274d2ef
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