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(Pro)renin receptor contributes to renal mitochondria dysfunction, apoptosis and fibrosis in diabetic mice

Recently we demonstrated that increased renal (Pro)renin receptor (PRR) expression in diabetes contributes to development of diabetic kidney disease. However, the exact mechanisms involving PRR activity and diabetic kidney dysfunction are unknown. We hypothesized that PRR is localized in renal mitoc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Caixia, Matavelli, Luis C., Akhtar, Safia, Siragy, Helmy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690878/
https://ncbi.nlm.nih.gov/pubmed/31406124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47055-1
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