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(Pro)renin receptor contributes to renal mitochondria dysfunction, apoptosis and fibrosis in diabetic mice

Recently we demonstrated that increased renal (Pro)renin receptor (PRR) expression in diabetes contributes to development of diabetic kidney disease. However, the exact mechanisms involving PRR activity and diabetic kidney dysfunction are unknown. We hypothesized that PRR is localized in renal mitoc...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Li, Caixia, Matavelli, Luis C., Akhtar, Safia, Siragy, Helmy M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690878/
https://ncbi.nlm.nih.gov/pubmed/31406124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47055-1
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