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A NONPEPTIDE ANGIOTENSIN II TYPE 2 RECEPTOR AGONIST PREVENTS RENAL INFLAMMATION IN EARLY DIABETES

We hypothesized that direct AT2R stimulation improves albuminuria in diabetes by preventing renal inflammation and improving oxidative stress. Normoglycemic controls (NC) and streptozotocin-induced diabetes Sprague-Dawley rats (DM) were treated for 4 weeks with vehicle (V) or the AT2R agonist Compou...

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Bibliografiske detaljer
Udgivet i:J Cardiovasc Pharmacol
Main Authors: Matavelli, Luis C., Zatz, Roberto, Siragy, Helmy M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390440/
https://ncbi.nlm.nih.gov/pubmed/25590749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000207
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