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A NONPEPTIDE ANGIOTENSIN II TYPE 2 RECEPTOR AGONIST PREVENTS RENAL INFLAMMATION IN EARLY DIABETES

We hypothesized that direct AT2R stimulation improves albuminuria in diabetes by preventing renal inflammation and improving oxidative stress. Normoglycemic controls (NC) and streptozotocin-induced diabetes Sprague-Dawley rats (DM) were treated for 4 weeks with vehicle (V) or the AT2R agonist Compou...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cardiovasc Pharmacol
Prif Awduron: Matavelli, Luis C., Zatz, Roberto, Siragy, Helmy M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390440/
https://ncbi.nlm.nih.gov/pubmed/25590749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000207
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