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Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.

To investigate the mechanisms of T-cell-mediated cytotoxicity, we estimated the involvement of apoptosis-inducing Fas molecule on the target cells and its ligand on the effector cells. When redirected by ConA or anti-CD3 monoclonal antibody, a CD4+ T-cell clone, BK1, could lyse the target cells expr...

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Detalhes bibliográficos
Main Authors: Hanabuchi, S, Koyanagi, M, Kawasaki, A, Shinohara, N, Matsuzawa, A, Nishimura, Y, Kobayashi, Y, Yonehara, S, Yagita, H, Okumura, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43903/
https://ncbi.nlm.nih.gov/pubmed/7515183
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