Cytotoxicity Mediated by the Fas Ligand (FasL)-activated Apoptotic Pathway in Stem Cells

Whereas it is now clear that human bone marrow stromal cells (BMSCs) can be immunosuppressive and escape cytotoxic lymphocytes (CTLs) in vitro and in vivo, the mechanisms of this phenomenon remain controversial. Here, we test the hypothesis that BMSCs suppress immune responses by Fas-mediated apopto...

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Détails bibliographiques
Auteurs principaux: Mazar, Julia, Thomas, Molly, Bezrukov, Ludmila, Chanturia, Alexander, Pekkurnaz, Gulcin, Yin, Shurong, Kuznetsov, Sergei A., Robey, Pamela G., Zimmerberg, Joshua
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Molecular Basis of Cell and Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755926/
https://ncbi.nlm.nih.gov/pubmed/19531476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032235
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