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Cytotoxicity Mediated by the Fas Ligand (FasL)-activated Apoptotic Pathway in Stem Cells

Whereas it is now clear that human bone marrow stromal cells (BMSCs) can be immunosuppressive and escape cytotoxic lymphocytes (CTLs) in vitro and in vivo, the mechanisms of this phenomenon remain controversial. Here, we test the hypothesis that BMSCs suppress immune responses by Fas-mediated apopto...

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Detalhes bibliográficos
Main Authors: Mazar, Julia, Thomas, Molly, Bezrukov, Ludmila, Chanturia, Alexander, Pekkurnaz, Gulcin, Yin, Shurong, Kuznetsov, Sergei A., Robey, Pamela G., Zimmerberg, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755926/
https://ncbi.nlm.nih.gov/pubmed/19531476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032235
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