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Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide

To study how MHC-associated self antigens may regulate the function of T cells in the periphery, we generated CD8+ T cell lines specific for a single residue variant of a self peptide. The self peptide (GAYEFTTL) was isolated from H-2-Kb class I MHC molecules immunopurified from tumor cells. CD8+ CT...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192615/
https://ncbi.nlm.nih.gov/pubmed/8676065
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