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Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide
To study how MHC-associated self antigens may regulate the function of T cells in the periphery, we generated CD8+ T cell lines specific for a single residue variant of a self peptide. The self peptide (GAYEFTTL) was isolated from H-2-Kb class I MHC molecules immunopurified from tumor cells. CD8+ CT...
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| Format: | Artigo |
|---|---|
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
1996
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192615/ https://ncbi.nlm.nih.gov/pubmed/8676065 |
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