Fas Ligand-Mediated Lysis of Self Bystander Targets by Human Papillomavirus-Specific CD8(+) Cytotoxic T Lymphocytes

Mouse cytotoxic T lymphocytes (CTL) reactive with a H-2D(b)-presented 9-mer peptide of the human papillomavirus type 16 protein E7(49-57) (RAHYNIVTF) were generated from the spleen cells of wild-type C57BL/6 (B6) or B6 perforin-deficient (B6.P(0)) mice. CD8(+) B6 CTL displayed peptide-specific perfo...

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Bibliographic Details
Main Authors: Smyth, Mark J., Krasovskis, Erika, Johnstone, Ricky W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110399/
https://ncbi.nlm.nih.gov/pubmed/9621057
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