Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.

To investigate the mechanisms of T-cell-mediated cytotoxicity, we estimated the involvement of apoptosis-inducing Fas molecule on the target cells and its ligand on the effector cells. When redirected by ConA or anti-CD3 monoclonal antibody, a CD4+ T-cell clone, BK1, could lyse the target cells expr...

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Библиографические подробности
Главные авторы: Hanabuchi, S, Koyanagi, M, Kawasaki, A, Shinohara, N, Matsuzawa, A, Nishimura, Y, Kobayashi, Y, Yonehara, S, Yagita, H, Okumura, K
Формат: Artigo
Язык:Inglês
Опубликовано: 1994
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC43903/
https://ncbi.nlm.nih.gov/pubmed/7515183
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