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Wnt-mediated protein stabilization ensures proper mitotic microtubule assembly and chromosome segregation

Wnt signaling stimulates cell proliferation by promoting the G1/S transition of the cell cycle through β-catenin/TCF4-mediated gene transcription. However, Wnt signaling peaks in mitosis and contributes to the stabilization of proteins other than β-catenin, a pathway recently introduced as Wnt-depen...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Stolz, Ailine, Neufeld, Kim, Ertych, Norman, Bastians, Holger
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388615/
https://ncbi.nlm.nih.gov/pubmed/25656539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439410
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