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Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation

The majority of human cancer shows chromosomal instability (CIN). Although the precise mechanism remains largely uncertain, proper progression of mitosis is crucial. B-type lamins were suggested to be components of the spindle matrix of mitotic cells and to be involved in mitotic spindle assembly; t...

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Bibliografische gegevens
Hoofdauteurs: Kuga, T, Nie, H, Kazami, T, Satoh, M, Matsushita, K, Nomura, F, Maeshima, K, Nakayama, Y, Tomonaga, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038388/
https://ncbi.nlm.nih.gov/pubmed/24637494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2014.6
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