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TRF1 Ensures the Centromeric Function of Aurora-B and Proper Chromosome Segregation

A cancer is a robustly evolving cell population originating from a normal diploid cell. Improper chromosome segregation causes aneuploidy, a driving force of cancer development and malignant progression. Telomeric repeat binding factor 1 (TRF1) has been established as a telomeric protein that negati...

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Detalhes bibliográficos
Main Authors: Ohishi, Tomokazu, Muramatsu, Yukiko, Yoshida, Haruka, Seimiya, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054313/
https://ncbi.nlm.nih.gov/pubmed/24752893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00161-14
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