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TRF1 Ensures the Centromeric Function of Aurora-B and Proper Chromosome Segregation
A cancer is a robustly evolving cell population originating from a normal diploid cell. Improper chromosome segregation causes aneuploidy, a driving force of cancer development and malignant progression. Telomeric repeat binding factor 1 (TRF1) has been established as a telomeric protein that negati...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054313/ https://ncbi.nlm.nih.gov/pubmed/24752893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00161-14 |
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