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Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation

Faithful chromosome segregation in mammalian cells requires the bi-orientation of sister chromatids which relies on sensing correct attachments between spindle microtubules and kinetochores. Although the mechanisms underlying cyclin-dependent kinase 1 (CDK1) activation that triggers mitotic entry is...

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Bibliografiska uppgifter
I publikationen:Nat Chem Biol
Huvudupphovsmän: Mo, Fei, Zhuang, Xiaoxuan, Liu, Xing, Yao, Phil Y., Qin, Bo, Su, Zeqi, Zang, Jianye, Wang, Zhiyong, Zhang, Jiancun, Dou, Zhen, Tian, Changlin, Teng, Maikun, Niu, Liwen, Hill, Donald L., Fang, Guowei, Ding, Xia, Fu, Chuanhai, Yao, Xuebiao
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798883/
https://ncbi.nlm.nih.gov/pubmed/26829474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2017
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