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Increased microtubule assembly rates mediate chromosomal instability in colorectal cancer cells
Chromosomal instability (CIN) is defined as the perpetual missegregation of whole chromosomes during mitosis and represents a hallmark of human cancer. However, the mechanisms causing CIN and its consequences on tumor growth are largely unknown. We identify an increase in microtubule plus end assemb...
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| Publié dans: | Nat Cell Biol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4389786/ https://ncbi.nlm.nih.gov/pubmed/24976383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2994 |
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