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Microtubule plus tips: A dynamic route to chromosomal instability

Although chromosomal instability (CIN) is a recognized hallmark of cancer the underlying mechanisms and consequences are largely unknown. However, it is accepted that lagging chromosomes represent a major prerequisite for chromosome missegregation in cancer cells. Here, we discuss how lagging chromo...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Stolz, Ailine, Ertych, Norman, Bastians, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905025/
https://ncbi.nlm.nih.gov/pubmed/27308411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.960768
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