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Wnt-mediated protein stabilization ensures proper mitotic microtubule assembly and chromosome segregation
Wnt signaling stimulates cell proliferation by promoting the G1/S transition of the cell cycle through β-catenin/TCF4-mediated gene transcription. However, Wnt signaling peaks in mitosis and contributes to the stabilization of proteins other than β-catenin, a pathway recently introduced as Wnt-depen...
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| Udgivet i: | EMBO Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388615/ https://ncbi.nlm.nih.gov/pubmed/25656539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439410 |
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