Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization

Crystallization chaperones are attracting increasing interest as a route to crystal growth and structure elucidation of difficult targets such as membrane proteins. While strategies to date have typically employed protein-specific chaperones, a peptide-specific chaperone to crystallize multiple cogn...

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Detalles Bibliográficos
Publicado en:Acta Crystallogr D Biol Crystallogr
Main Authors: Johnson, Jennifer L., Entzminger, Kevin C., Hyun, Jeongmin, Kalyoncu, Sibel, Heaner, David P., Morales, Ivan A., Sheppard, Aly, Gumbart, James C., Maynard, Jennifer A., Lieberman, Raquel L.
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2015
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388267/
https://ncbi.nlm.nih.gov/pubmed/25849400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715001856
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