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Biophysical characterization and structure of the Fab fragment from the NIST reference antibody, RM 8671

Monoclonal antibody pharmaceuticals are the fastest-growing class of therapeutics, with a wide range of clinical applications. To assure their safety, these protein drugs must demonstrate highly consistent purity and stability. Key to these objectives is higher order structure measurements validated...

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Detalhes bibliográficos
Publicado no:Biologicals
Main Authors: Karageorgos, Ioannis, Gallagher, Elyssia S., Galvin, Connor, Gallagher, D. Travis, Hudgens, Jeffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856035/
https://ncbi.nlm.nih.gov/pubmed/28965821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biologicals.2017.09.005
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